Collagenase Total Occlusion-1 (CTO-1) Trial
نویسندگان
چکیده
منابع مشابه
The Collagenase Total Occlusion - 1 ( CTO - 1 ) Trial : A Phase I , Dose Escalation , Safety Study
Background-Percutaneous interventions for chronic total occlusions (CTO) have low success
متن کاملCollagenase Total Occlusion-1 (CTO-1) trial: a phase I, dose-escalation, safety study.
BACKGROUND Percutaneous interventions for chronic total occlusions have low success rates, primarily because of failure of guide wire crossing. Collagen-rich matrix constitutes the main barrier to chronic total occlusion crossing. In preclinical studies, local delivery of a bacterial collagenase formulation improved guide wire crossing. The Collagenase Total Occlusion-1 (CTO-1) Trial is a phase...
متن کاملThe Collagenase Total Occlusion - 1 ( CTO - 1 ) Trial : A Phase I , Dose Escalation , Safety Study Running title :
Background-Percutaneous interventions for chronic total occlusions (CTO) have low success
متن کاملPercutaneous. Recanalization of Chronic Total Occlusion (CTO) Coronary Arteries: Looking Back and Moving Forward
Chronic total occlusion (CTO) of coronary arteries is one of the most challenging PCI, usual‐ ly defined as more than three-month-old obstruction of a native coronary artery. This coro‐ nary lesion subset is a frequent finding in patients with coronary artery disease (CAD) as CTOs have been reported in approximately one-third of patients undergoing diagnostic cor‐ onary angiography. However onl...
متن کاملAcute outcome of chronic total occlusion (CTO) recanalizsation in the elderly.
OBJECTIVES Percutaneous coronary intervention (PCI) of total chronic total occlusion (CTO) still remains a major challenge in interventional cardiology. There is only insignificant knowledge reported in the literature about age differences in CTO recanalization. We analyzed in this study the issue of the impact of age on procedural characteristics, complications and short-term outcome. METHOD...
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ژورنال
عنوان ژورنال: Circulation
سال: 2012
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.111.063198